Friday, October 3, 2014

Search for newer antibiotics – Crawling back to Mother Nature's Laps!

Contributed by Akilesh Ramasamy in association with A.J. Tamhankar
“Antibiotic resistance is not a threat looming over the horizon. It's here, right now ....”
- Margaret Chan, Director Genreral, WHO
BeesIn South Africa, tuberculosis resistant to all known antitubercular agents is prevalent. Multiple Drug Resistant (MDR) cases of tuberculosis is not unknown in India. Even doctors have succumbed to MDR-TB, the death of an intern from Sion Hospital due to MDR-TB in 2013 is a case in point. (News Source: TOI, 1 July, 2013) Residents, interns, nurses and even dentists of civic hospitals have been known to be victims of tuberculosis with some of them developing MDR-TB. (News Source: Mid-Day 31 Dec. 2013 )

Friday, September 26, 2014

Interview with Dr. A.J Tamhankar, National Co-ordinator, IIMAR in Inter Press Service by Ranjita Biswas

News Story by Ranjita Biswas in INTER PRESS SERVICE News agency containing excerpts from an Interview with Dr. A.J. Tamhankar, National Coordinator, IIMAR.

India: A Race to the Bottom with Antibiotic Overuse

India consumed about 12.9 billion units of antibiotics in 2010.

Read further here at IPS News, 2014

Wednesday, August 6, 2014

Low Cost Device for Rapid testing of Antibiotic Resistance developed in India by BITS professor & her student

Contributed by Akilesh. R and A.J. Tamhankar

A low Cost Device for Rapid testing of Antibiotic Resistance developed in India by BITS professor Dr. Suman Kapur and her student Anuradha P

World Health Organization (WHO) considers antibiotic resistance as one of the three greatest public health threats today. Ensuring availability of effective antibiotics is a highly prioritized area for low- and middle-income countries, where the infectious disease burden is high and access to healthcare is not easy and also not affordable for many.

Sunday, July 20, 2014

Government of India, issues a notice on Irrational use of antibiotics in animal/livestock

Contributed by  Akilesh. R and Ashok J. Tamhankar 
Central Drugs Standard Control Organisation (CDSCO),  Government of India, issues a  notice on Irrational use of antibiotics in animal/livestock – A source of spread of antibiotic resistance in humans!
While antibiotic use and abuse in humans has been given due notice in recent times, the other potential source of spread of antibiotic resistance to humans is through animal products which has not been given due regard. Besides therapy antibiotics are used in animals particularly in poultry farming as growth promoters. The use in animals is also a precursor of antibiotic resistance; both through the animal food products as well as the faeces that go into the environment, as nearly 50 % of antibiotics given to animals are excreted within 24 hours.  While in many countries use of antibiotics is banned as growth promoters, it is not so in India. Government of India has now started to take action on this issue. Central Drugs Standard Control Organisation (CDSCO),  Government of India has issued notice in this regard to Drug controllers of all states and union territories in June 2014. The circular in this context generally says the following.

Thursday, April 3, 2014




Report on Antibiotic Resistance Threats in the United States, (2013, CDC Report)

 
This report provides a unique look at the threats that are posed by antibiotic resistant bacteria to public health. Though the report talks of US, essentially the same applies everywhere.  Similar things are happening in every society.
Every year, more than two million people are infected in the US with some bacterium that is resistant to antibiotics, and more than 20,000 people die every year due to such infections. Many more Americans die every year from conditions that are complicated by an infection that is resistant to antibiotics. The condition in economically disadvantaged countries will be more disastrous.
Data indicates that most infections that are resistant to antibiotics occur in the general US community, but many deaths that have something to do with antibiotic resistance can occur in health care settings, including nursing homes and hospitals.
The report is a good reference for anyone who needs information about resistance to antibiotics. It is designed to be easy to access for many different audiences. It covers many types of bacteria that can cause severe infections in humans, and the antibiotics that are currently used to treat such infections. Also, Candida, which is a fungus that can cause serious illnesses, also is included because it is showing a higher resistance to drugs that are being used for treatment.
The introduction of the CDC report states that infections that are resistant to antibiotics can cause serious and avoidable costs to an overburdened health care system. In many cases, these infections require longer and more expensive treatments, longer hospital stays, more doctor visits and hospital visits, and the result is more death and disability when compared to infections that can be treated with antibiotics. The total cost to the economy of antibiotic resistance in the US has been hard to figure, but estimates are as high as $20 billion in extra health care costs, and $35 billion a year for additional costs to society in terms of lost productivity.
Antibiotic use is the most important reason that antibiotic resistance is increasing around the world. Antibiotics are some of the most frequently prescribed drugs that are used in human medicine. However, as much as 50% of all antibiotics that are prescribed are not needed, or are not as effective as they are prescribed to be.
Antibiotics also are often used in animal feed to prevent disease, and to promote growth of animals that produce food. Antibiotic use to promote growth is not needed, the CDC report states, and the practice should be stopped.
Another major reason for the growth of antibiotic resistance is the increase of resistant strains of many types of bacteria that are spread from one person to the other, or from sources that are non human in our environment, including food.
There are four actions that the report states will help to fight such deadly infections:
·  Stop infections and stop the spread of  resistance
·         Track bacteria that are resistant to antibiotics
·         Improve use of antibiotics in medicine
·         Promote the growth of new antibiotics, and develop new tests for resistant bacteria
The report states that while many bacterial resistance problems are serious, gram-negative pathogens are a serious problem. They are getting more resistant to all types of drugs that may be considered for treatment. The report notes that the most serious infections are associated with health care, and the most common ones are Enterobacteriaceae, pseudomonas aeruginosa, and acinetobacter.

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